Software for Digital Histology

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our-business

Our business

HS Analysis provides tissue analysis software for digital pathology and microscopy images.
Get best practice analysis solutions derived with state of the art artificial neural networks / Deep Learning to automate quantification of your images.

technology

Technology

The most up-to-date artificial intelligence is one key technology of automatic interpretation of tissue samples in the software of HS-Analysis. Technically speaking, virtual slides are analyzed with deep learning. Virtual slides are digital images, that are produced by microscope roboters called slide scanner. In this way you quickly get quantitative results about effects of drug candidates on tissue.

Specialists of HS-Analysis use the appropriate technology depending on requirements of customers.
Two examples of most used technologies are listed below.

Digital pathology is a promising method for quantitative automatization in pharmaceutical research. The key technology was the introduction of Whole-Slide Imaging (WSI) with digital slide scanners. They allow virtualization of the whole slide with large tissue sections in high microscopic resolution. Combination of WSI with automatic detection and quantification software enables numerous new possibilities and methods to search for drugs against diseases. HS-Analysis develops automatic WSI quantification solutions for efficient workflows in pharmaceutical research. Solutions are compatible with all slide scanner file formats.
Recent evolution in artificial neural networks allows reliable recognition of structures with complex morphology traits, similar like the human brain does. HS-Analysis specialized in neural network applications and Deep Learning to detect your Region of Interest in automatic manner. Avoid manual annotations for ROI definition to achieve high throughput with short analysis times.
scope

Scope

Our quality standards apply also in terms of service, technical expertise and advice.
Our dedicated employees are happy to assist you with know-how and experience in your daily business.

  • 3D reconstruction & analysis of serial slides.

    Anatomy

    3D reconstruction & analysis of serial slides.
  • Detection of frequency and distribution of IHC labeled blood vessels (e.g. as indicator of tumor malignancy).

    Angiology

    Detection of frequency and distribution of IHC labeled blood vessels (e.g. as indicator of tumor malignancy).
  • Glomeruli detection & analysis of interstitial fibrosis in Kidney.

    Nephrology

    Glomeruli detection & analysis of interstitial fibrosis in Kidney.
  • Quantification of labeled parameters in skin.

    Dermatology

    Quantification of labeled parameters in skin.
  • Analysis of gut wall and gut villi & crypt.

    Gastroenterology

    Analysis of gut wall and gut villi & crypt.
  • 3D Analysis of Brain structures and Plaque Analysis in Alzheimer´s disease.

    Neuroscience

    3D Analysis of Brain structures and Plaque Analysis in Alzheimer´s disease.
  • Alveoli analysis in lung tissue.

    Pneumology

    Alveoli analysis in lung tissue.
  • Quantification of proliferation markers like Ki-67, p21, p53, Stathmin, H-Scoring etc.

    Oncology

    Quantification of proliferation markers like Ki-67, p21, p53, Stathmin, H-Scoring etc.
  • Osteon quantification, Osteocytes, Haversian Canal, Volkman’s Canal

    Osteology

    Osteon quantification, Osteocytes, Haversian Canal, Volkman’s Canal
  • 3D reconstruction & analysis of serial slides.

    Anatomy

    3D reconstruction & analysis of serial slides.
  • Detection of frequency and distribution of IHC labeled blood vessels (e.g. as indicator of tumor malignancy).

    Angiology

    Detection of frequency and distribution of IHC labeled blood vessels (e.g. as indicator of tumor malignancy).
  • Glomeruli detection & analysis of interstitial fibrosis in Kidney.

    Nephrology

    Glomeruli detection & analysis of interstitial fibrosis in Kidney.
  • Quantification of labeled parameters in skin.

    Dermatology

    Quantification of labeled parameters in skin.
  • Analysis of gut wall and gut villi & crypt.

    Gastroenterology

    Analysis of gut wall and gut villi & crypt.
  • 3D Analysis of Brain structures and Plaque Analysis in Alzheimer´s disease.

    Neuroscience

    3D Analysis of Brain structures and Plaque Analysis in Alzheimer´s disease.
  • Alveoli analysis in lung tissue.

    Pneumology

    Alveoli analysis in lung tissue.
  • Quantification of proliferation markers like Ki-67, p21, p53, Stathmin, H-Scoring etc.

    Oncology

    Quantification of proliferation markers like Ki-67, p21, p53, Stathmin, H-Scoring etc.
  • Osteon quantification, Osteocytes, Haversian Canal, Volkman’s Canal

    Osteology

    Osteon quantification, Osteocytes, Haversian Canal, Volkman’s Canal
projects-two

Projects

Research experts in pharmacology, bioscience and in university medical centers are permanently expected to increase efficiency and reduce timeinvest and cost.

HS-Analysis delivers software solutions for precise image analysis. In that way the researcher is going to be supported to get qualitative and reproducible data.

The system reduces human errors, which are possible in manual evaluation. It finally allows to get Big Data results in a short time and at the end to analyse, manage and present them. That allows researchers to fulfill continuously increasing expectations concerning efficiency and output of results.

details

Annotation Software to set region of interests (ROI)

Manual drawing of regions of interest (ROI) as well as automatic ROI detection. Image analysis can be restricted to ROIs or different analysis methods can be allocated to different ROI types within one image.

Screening with oncology markers

Tissue evaluation with cancer specific markers, for example Ki67, p21, p53, Stathmin, bTubulin, etc.

TMA Screening & Analysis

Analysis Software for Tissue MicroArrays (TMA) with variable number of cores. Semi automatic naming of TMA cores. Export of TMA core results together with cores names into excel files.

Blood vessel analysis

Blood vessels can be marked with immunohistochemistry. This allows blood vessel counting and analysis of blood vessel distribution.

Kidney glomeruli detection & fibrosis evaluation

Software for automatic detection of kidney glomeruli and evaluation of fibrotic structures within glomeruli. Analysis of interstitial fibrosis.

services

Services

HS-Analysis works closely with you to develop target-oriented software solutions.

You get modular and scalable solutions for efficient analysis of histological studies.

That reduces time and cost and increases return on equity.

Get the right solutions for your requirements and be beyond the market leaders in your area.

HS-Analysis is a company that is established in the pharmaceutical industry with proven software solutions.

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Management board

Sergey Biniaminov
Dipl.rer.pol.techn.
CEO / Co-Founder

David Haumann
Dipl.-Biol.
CEO / Co-Founder

Thomas Schenker
Dipl.-Inform.
CEO / Co-Founder

The three shareholders got together at KIT (Karlsruhe Institute of Technology) and pursue the aim, to set standards in automatic analysis in Big Data.

Together with their team they believe  that they are well prepared for rapid growth and sustainable development of the company and create a good environment for new projects.

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